01
Clinical-Grade MSC Manufacturing Platform
Citospin’s foundation is a clinically validated mesenchymal stromal cell (MSC) manufacturing platform built within the first clean room in Spain dedicated exclusively to Advanced Therapy Medicinal Products (ATMPs). Operating under full GMP conditions since 2011, our platform combines scientific expertise with pharmaceutical-grade process control.
02
Bone Marrow–Derived MSCs
We specialize in the isolation, expansion, and release of bone marrow–derived MSCs for clinical use. Our platform supports both:
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Autologous manufacturing, tailored to individual patients
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Allogeneic production, enabling expanded therapeutic strategies
Products may be released fresh or cryopreserved, depending on clinical requirements. All manufacturing processes are supported by validated quality controls, sterility assurance systems, and full batch traceability in accordance with EU ATMP regulations.
03
Clinical Experience
To date, Citospin has manufactured MSC treatments for more than 3,000 patients across multiple therapeutic indications and has supported over 20 clinical trials as GMP manufacturer and, in selected programs, clinical sponsor.
This experience provides a robust operational framework built on reproducibility, regulatory compliance, and clinical execution.
04
Infrastructure & Quality
Our GMP infrastructure integrates:
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Controlled clean room environments
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Standardized expansion protocols
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In-process controls and release testing
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Comprehensive documentation and traceability systems
The platform is designed to ensure consistent product quality while maintaining flexibility to adapt to different clinical programs.